| Name | Bacillus coagulans |
| Synonyms | Bacillus coagulis Bacillus coagulans Bacillusdede coagulans Bacillus Ferment Filtrate Extract |
| CAS | 68038-65-3 |
| EINECS | 924-436-4 |
| Use | Bacillus coagulans (Bacillus coagulans), a gram-positive bacterium, belongs to the genus Bacillus of the phylum Sclerobacterium taxonomically. Its cells are rod-shaped, terminal spores, no flagella, and can decompose sugars to produce L-lactic acid. |
It was found that in the early 19th century, Bacillus coagulans was first isolated and described in detail in 1932 due to the large-scale condensation of condensed milk and the rancidity and deterioration of tomatoes, potatoes and other products. Since its development, many studies have shown that Bacillus coagulans, as a unique new type of spore probiotics, not only has the lactic acid-producing characteristics of lactic acid bacteria, but also has the rich enzyme system of Bacillus, strong stress resistance, high temperature and high pressure resistance, stable storage characteristics.
Product characteristics With the deepening of research on Bacillus coagulans, its characteristics are gradually known. This bacteria is a gram-positive bacteria, belonging to the phylum Pachyomycetes. The vegetative cells are rod-shaped and have certain motility. It can ferment glucose, sucrose, maltose, mannitol, raffinose, and trehalose to produce acid without gas. It can hydrolyze starch and casein. This bacterium is catalase positive, lacks cytochrome C oxidase and the ability to degrade nitrate to nitrite. The colony morphology is opaque white, round, with prominent surface. Its spores are terminal and oval. Bacillus coagulans can grow in both aerobic and anaerobic environments, but the amount of lactic acid produced under aerobic conditions is significantly lower than that under anaerobic conditions, while the biomass is just the opposite, which indicates that the oxygen content in the environment can change some metabolic pathways of the bacteria.
Mechanism of action Bacillus coagulans can regulate the structure of the intestinal flora, increase the number of beneficial bacteria in the intestine, produce bacteriocins through self-metabolism to inhibit and eliminate pathogenic antigens, enhance the viability of epithelial cells and build a complete biological barrier system, Stimulate the secretion of antibodies and anti-inflammatory cytokines, enhance the immune response of symbiotic bacteria, thereby effectively enhancing intestinal mucosal immunity, thereby improving the intestinal microenvironment.